Doxorubicin hydrochloride



Doxorubicin hydrochloride

Product name:Doxorubicin hydrochloride
Molecular Formula:C27H30ClNO11
Formula Weight:579.98
Description:Doxorubicin suitable to be orange-red crystalline powder; It is hygroscopic. Dissolved in water, slightly dissolved in methanol.

Suitable amount of Doxorubicin hydrochloride was used to dissolve and dilute the mobile phase to prepare a solution containing approximately 1.0mg per 1ml, as the test solution; Take the right amount and make a solution containing about 10 mug per 1ml by quantitative dilution of mobile phase as the control solution. According to the chromatographic conditions under the content determination, take the control solution 10mul injection into the liquid chromatograph, adjust the detection sensitivity, so that the peak height of the main component chromatograph peak is about 30% of the full range, then accurately take the test solution and control solution 10mul, respectively into the liquid chromatograph, record the chromatographic diagram to the main component peak retention time 3.5 times. If there is an impurity peak in the chromatographic diagram of the sample solution, the area of single impurity peak shall not be greater than 0.5 times (0.5%) of the main peak area of the control solution, and the sum of the peak area of all impurities shall not be greater than 2 times (2.0%) of the main peak area of the control solution.
Melting point:216 °C (dec.)(lit.)
Flash Point:443.8 °C
Chemical property:Orange-Red Crystalline Solid
Use:For the treatment of chronic leukemia,acute leukemia and malignant lymphoma.


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