Sulfadiazine is a sulfonamide antibiotic.
It eliminates bacteria that cause infections by stopping the production of folic acid inside the bacterial cell, and is commonly used to treat urinary tract infections (UTIs).
In combination, sulfadiazine and pyrimethamine, can be used to treat toxoplasmosis, a disease caused by Toxoplasma gondii.
Sulfadiazine is white or white - like crystal or powder; Odorless, tasteless; Meets the light color gradient dark. Sulfadiazine is slightly soluble in ethanol or acetone and almost insoluble in water. It is soluble in sodium hydroxide solution or ammonia solution and dissolved in dilute hydrochloric acid.
About 0.1g of Sulfadiazine was taken, 3ml of each solution of water and 0.4% sodium hydroxide was added, dissolved by shaking, and filtered. The filtrate was taken, and 1 drop of copper sulfate test solution was added to generate yellow-green precipitation, which turned purple after being placed.
Take sulfadiazine2.0g, add 100ml water, heat it for 10 minutes in the water bath, cool it immediately, and strain; Take 25ml filtrate, add 2 drops of phenolphthalein indicator solution and 0.20ml of sodium hydroxide titration solution (0.1mol/L), which should be pink.