Potassium benzylpenicillin has a good antibacterial effect against Streptococcus such as Streptococcus hemolyticus, Streptococcus pneumoniae and Staphylococcus which does not produce penicillinase. Has a moderate antibacterial effect on Enterococcus. Neisseria gonorrhoeae, Neisseria meningitidis, Corynebacterium diphtheriae, Bacillus anthracis, Actinomycetes, Streptomyces faecalis, Listeria, Leptospira and Treponema pallidum are sensitive to this product. This product also has certain antibacterial activity against Haemophilus influenzae and B. pertussis. Other Gram-negative aerobic or facultative anaerobic bacteria have poor sensitivity to this product. Potassium benzylpenicillin has good antibacterial activity against Clostridium, Digestive Streptococcus anaerobic bacteria and Bacteroides-producing Bacillus, and has poor antibacterial activity against Bacteroides fragilis. Penicillin exerts a bactericidal action by inhibiting bacterial cell wall synthesis.
