Use of bacitracin

Asia Bio-Pharmaceutical Research Institute
Submitted by xulijin on Tue, 09/17/2019 - 03:06

Bacitracin is suitable for the treatment of infections such as sputum, abscess, acne, purulent skin disease, Ami dysentery, Neisseria gonorrhoeae and meningitis. It is more toxic to the kidneys.
Bacitracin is mainly added to feed as an animal growth promoter. Since zinc, cadmium and mercury salts are present, the activity of the product is enhanced, so the zinc salt and manganese salt of the product are often used as feed additives. Growth promoters are non-nutritive additives that stimulate the growth of livestock, increase the rate of weight gain and feed utilization, and improve the health of livestock. Bacitracin has a strong antibacterial effect on most Gram-positive bacteria, antibacterial is similar to penicillin, and is also effective against penicillin-resistant Staphylococcus aureus. Bacitracin is mainly used as a medicine for treating various infections caused by Staphylococcus aureus, such as sepsis, pneumonia, endocarditis and the like. It is suitable for the treatment of sputum, abscess, acne, purulent skin disease, Ami dysentery, Neisseria gonorrhoeae and meningitis and cocci. It is more toxic to the kidneys. Zinc peptide is very effective against Gram-positive bacteria, and is also effective against some Gram-negative bacteria spirochetes and radiobacteria. In addition, it can promote the growth of livestock and poultry. It can be used for pig feed under 4 months old, and the dosage is 4 (16.8×104U)-40(168×104U) g/t; it can be used for chicken feed under 16 weeks old, the dosage is 4-20g/t; it can be used for 3 Cattle feed below 10 months old is 10-100g/t; it can also be used for cattle feed below 6 months old, dosage 4-40g/t.
Bacitracin is a polypeptide antibiotic produced by Bacillus licheniformis. Used to study the biosynthesis of peptidoglycan and the metabolic level of isoprene to disrupt the synthesis of bacterial cell walls. Also used to study the biosynthesis of sterols and squalene.