Bendazac L-lysine

Asia Bio-Pharmaceutical Research Institute

Bendazac L-lysine

Product name:Bendazac L-lysine
CAS: 81919-14-4
Molecular Formula: C22H28N4O5
Molecular Weight: 428.48
Product description:Rabbit after intravenous injection, in the eye tissue and plasma can be measured technical and its metabolites) - 5 - hydroxy benzoic acid (5 - BDZ), including the iris were highest, followed by other ciliary body, retina and cornea, tear, aqueous humor and vitreous body and the lens. Plasma and elimination half-life of aqueous humor and vitreous, ciliary body, retina (T1/2? 2.47, 4.56, 3.59, and 3.22 hours respectively, and the lens in the T1/2? 17.1 hours, significantly longer than other groups. By 14 c - 0.5% BDZL eye drops, a drop after use, the eyes can be detected in the organization drugs, the longest residence time in the lens.The goods is aldose reductase (AR) inhibitors, the literature has inhibitory effect on the lens AR, so use benzyl of lysine (BDZL) eye drops are activated to restrain activity of AR in the eyes, achieve the goal of prevention or treatment of cataract.

 

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