Product name:Human advanced oxidation protein products,AOPP ELISA Kit
Description:
Advanced oxidation protein products (AOPP) are markers of oxidant-mediated protein damage in ESRD. AOPP also behaved as mediators of inflammation. The study in a cohort of 162 uremic patients showed that plasma concentrations of AOPP increased with progression of chronic renal failure and were closely related to advanced glycation end products (AGE)-pentosidine, taken as a marker of AGE. In vivo, the relevance of AOPP and AGEpentosidine in monocyte-mediated inflammatory syndrome associated with uremia was evidenced by close correlations between AOPP or AGE-pentosidine and monocyte activation markers, including neopterin, IL-1R antagonist, TNF-a, and TNF soluble receptors (TNF-sR55 and TNF-sR75).