Clindamycin hydrochloride

Asia Bio-Pharmaceutical Research Institute

Clindamycin hydrochloride

Product name:Clindamycin hydrochloride
CAS:21462-39-5
Molecular Formula:C18H34Cl2N2O5S
Formula Weight:461.44
Specification:5g
Description:Clindamycin suitable for white crystalline powder. Easily soluble in water, soluble in methanol, pyridine, slightly soluble in ethanol, almost insoluble in acetone or chloroform, odorless, bitter taste.

Clindamycin hydrochloride is quite suitable to be used as a semi-synthetic antibiotic, characterized by its extensive antibacterial spectrum and strong antibacterial activity, and its obvious antibacterial activity to gram-positive bacteria, so it can effectively kill staphylococcus, anaerobic bacteria, pneumococci and streptococcus. Pneumocystis, toxoplasma, plasmodium falciparum and other pathogenic parasites have active effects, and adverse reactions are small. Clindamycin hydrochloride, clindamycin phosphate and clindamycin palmitate are currently used in clinical products, among which clindamycin phosphate and clindamycin palmitate have no antibacterial activity, and play an antibacterial and anti-parasite role after metabolizing clindamycin in vivo.

Clindamycin hydrochloride is quite suitable for lincomycin; its antibacterial spectrum is more extensive than lincomycin, and its antibacterial activity is 4-8 times higher than lincomycin. It has antibacterial activity to aerobic bacteria, staphylococcus and streptococcus of gram positive, and also has antibacterial activity to mycoplasma, chlamydia and a variety of anaerobic bacteria.

 

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