Product name:Hyaluronidase
CAS:37326-33-3
Specification:100mg
Description:
The hyaluronidases (EC 3.2.1.35) are a family of enzymes that degrade hyaluronic acid.
In humans, there are six associated genes, including HYAL1, HYAL2, HYAL3, and PH-20/SPAM1.
By catalyzing the hydrolysis of hyaluronic acid, a major constituent of the interstitial barrier, hyaluronidase lowers the viscosity of hyaluronic acid, thereby increasing tissue permeability. It is, therefore, used in medicine in conjunction with other drugs to speed their dispersion and delivery. The most common application is in ophthalmic surgery, in combination with local anesthetics. It also increases the absorption rate of parenteral fluids given by hypodermoclysis, and is an adjunct in subcutaneous urography for improving resorption of radiopaque agents. Hyalurodinase is also used for extravasation of hyperosmolar solutions. Usually a 0.2 ml dose of the drug is injected around the area of extravasation. A total of 1 ml is used.