Product name:Oligomycin
CAS:1404-19-9
Molecular Formula:C45H74O11
Specification:5mg
Description:
Oligomycins are macrolides created by Streptomyces that can be poisonous to other organisms.
They have use as antibiotics.
In addition, oligomycin inhibits ATP synthase by blocking its proton channel (Fo subunit), which is necessary for oxidative phosphorylation of ADP to ATP (energy production). Electron transport continues but there is an increase in the proton gradient, and electron transport soon stops because of the difficulty of pumping any more protons against the steep gradient.
Administering oligomycin to an individual can result in very high levels of lactate accumulating in the blood and urine.