Product name:Ribonuclease A
CAS:9001-99-4
Specification:100mg
Description:
Ribonuclease A (RNase A) is a pancreatic ribonuclease that cleaves single-stranded RNA. Bovine pancreatic RNase A is one of the classic model systems of protein science.
The positive charges of RNase A lie mainly in a deep cleft between two lobes. The RNA substrate lies in this cleft and is cleaved by two catalytic histidines, His12 and His119, via a 2'-3' cyclic phosphate intermediate that is stabilized by nearby lysines such as Lys7, Lys41 and Lys66.