Fluoroquinolones

Asia Bio-Pharmaceutical Research Institute

Fluoroquinolones

Product name:Fluoroquinolones
CAS: 86393-33-1
Molecular Formula: C13H9ClFNO3
Molecular Weight: 281.67
Product description:(1) wide antimicrobial spectrum, strong antibacterial activity, especially for the antimicrobial activity of high G - bacillus and including many drug-resistant strains such as MRSA (methicillin-resistant s. aureus bacteria) has good antibacterial effect; (2) the incidence of drug resistance is low, there are plasmid mediated resistance; (3) the body wide distribution, high concentrations of organization, can reach effective antibacterial and bactericidal concentration; (4) most of the department of oral preparations, injection, a longer half-life, use less, easy to use; (5) for all chemical synthetic medicine, price is antibiotic treatment is low, stable performance, less adverse reaction. So this kind of medicine become the most rapid development in the chemical synthesis of anti-infection drugs, has become a main chemotherapy drugs in the clinical treatment of bacterial infectious diseases. 6 quinolone classes and other antimicrobials point is different, they with bacteria deoxyribonucleic acid (DNA) as a target. Bacteria double twisted strands of DNA to become loops or spiral (called super screw), the DNA form superhelix enzyme called DNA cyclotron, quinolone hinder

 

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