Product name:Limaprost
CAS: 88852-12-4
Molecular Formula: C22H36O5
Molecular Weight: 380.523
Product description:White crystal, melting point 97 ~ 100 ℃.88 mg of compound (I) and 88 mg4 - dimethyl amine pyridine soluble in methylene chloride, under the ice bath cooling methanesulfonyl chloride to join 116 feet. Never put off till tomorrow what you can, at 30 ℃ 2.5 h reaction, get 94% of the compounds (Ⅱ). 80 mg of compounds (Ⅱ) and contains 800 mg of zinc in acetic acid isopropyl alcohol, 50 ℃ in 2 h reaction, get 66% of the compounds (Ⅲ). Acid (such as trifluoroacetic acid or methyl sulfonic acid) hydrolysis for compounds (Ⅳ), with pig liver esterase hydrolysis, finally get Limaprost.A beneficial effect on peripheral circulation, ring phosphoric acid contents of platelet have inhibitory effect on thromboxane production. Used in occlusive thrombus vasculitis and concurrent ischemic symptoms such as ulcer, pain and cold feeling.