Product name:Tiagabine hydrochloride
CAS: 145821-59-6
Molecular Formula: C20H26ClNO2S2
Molecular weight:412.0089
Appearance:white powder
Stability:Stable
Shelf life:2 years
Product description :Tiagabine Hydrochloride is the hydrochloride salt form of tiagabine, a nipecotic acid derivative with anticonvulsant property. Tiagabine hydrochloride inhibits the gamma-aminobutyric acid (GABA) transporter type 1 (GAT1), which is predominantly localized in presynaptic terminals of neurons thereby preventing the reuptake of GABA by the presynaptic endings. Consequently, this increases the level of available GABA within the synaptic cleft, thereby resulting in prolongation of its inhibitory actions.