Product name:Demecolcine
CAS:477-30-5
Molecular Formula:C21H25NO5
Formula Weight:371.43
Specification:1g
Description:
Demecolcine is a drug used in chemotherapy.It is closely related to the natural alkaloid colchicine with the replacement of the acetyl group on the amino moiety with methyl.
During cell division Demecolcine inhibits mitosis at metaphase by inhibiting spindle formation. Medically Demecolcine has been used to improve the results of cancer radiotherapy by synchronising tumour cells at metaphase, the radiosensitive stage of the cell cycle.